Fresh-water dinoflagellates of Maryland

Collections were made in the summer of 1942 and again at different times in 1946 and 1947. Some collections were not sufficient in numbers to allow for proper identification, so the present paper does not give a complete list. Of the 20 identified species reported on in the paper, two are new to science and ten have not been reported previously for the United States

Nickel Impregnated Cerium-Doped Strontium Titanate Fuel Electrode: Direct Carbon Dioxide Electrolysis and Co-Electrolysis

Direct electrolysis of carbon dioxide and co-electrolysis of steam and carbon dioxide offers an efficient and effective method to produce CO or syngas and also utilizes CO2 in a carbon-neutral fuel cycle. Here we report the use of composite fuel electrode containing a Sr0.7Ce0.2TiO3±δ (SCT) and Sm0.20Ce0.80O2-δ (SDC) backbone which has been infiltrated with nickel nitrate and decomposed to form nickel surface decoration on the ceramic scaffold. Maximum cell current during electrolysis at 850◦C was 263 mAcm−2 and 192 mAcm−2 at 1.8V for co-electrolysis and CO2, respectively. The infiltrated nickel particles provided a large surface area and enhanced activity during electrolysis. These findings demonstrate that Ce-doped titanate mixed conductors combined with low volume nickel additions are promising next-generation electrode materials for solid oxide electrolysis cells

Ventilation of small livestock trailers

A large number of livestock is transported to market in small box trailers. The welfare of animals transported in this way is now assuming greater importance with the onset of tougher EU legislation. This paper presents the first study into the ventilation of small livestock trailers using experimental and computational methods. Wind tunnel studies, using a 1/7th scale model, highlight the important influence of the towing vehicle and trailer design on the airflow within the trailer. Detailed CFD analysis agrees well with the wind tunnel data and offers the ability to assess the impact of design changes

Chronic intrauterine hypoxia interferes with aortic development in the late gestation ovine fetus

This study explored arterial remodelling in fetuses growth restricted by hypoxia. Chronically catheterized fetal sheep were made moderately or severely hypoxic by placental embolization for 15 days starting at gestational age 116-118 (term ∼147 days). Cross-sections of the aorta were analysed for collagen and elastin content using histological procedures, while immunofluorescence was applied to measure markers of vascular smooth muscle cell (VSMC) type. In frozen aortae quantitative PCR was used to measure mRNA levels of extracellular matrix (ECM) precursor proteins as well as molecular regulators of developmental and pathological remodelling. Relative to Control (n= 6), aortic wall thickness was increased by 23% in the Moderate group (n= 5) and 33% (P \u3c 0.01) in the Severe group (n= 5). Relative to Control, the Severe group exhibited a 5-fold increase in total collagen content (P \u3c 0.01) that paralleled increases in mRNA levels of procollagen I (P \u3c 0.05) and III and transforming growth factor β (TGF-β 1) (P \u3c 0.05). The percentage area stained for α-actin was inversely related to fetal arterial oxygen saturation (P \u3c 0.05) and total α-actin content was 45% higher in the Moderate group and 65% (P \u3c 0.05) higher in the Severe group, compared to Control. A 12% and 39% (P \u3c 0.05) reduction in relative elastic fibre content was observed in Moderate and Severe fetuses, respectively. mRNA levels of the elastolytic enzyme, matrix metalloproteinase-2 (MMP-2) were inversely correlated with fetal arterial oxygen saturation (P \u3c 0.05) (Fig. 7) and mRNA levels of its activator, membrane-type MMP (MTI-MMP), were elevated in the Severe group (P \u3c 0.05). Marked neointima formation was apparent in Severe fetuses (P \u3c 0.05) concomitant with an increase in E-selectin mRNA expression (P \u3c 0.05). Thus, aberrant aortic formation in utero mediated by molecular regulators of arterial growth occurs in response to chronic hypoxaemia. © 2011 The Authors. Journal compilation © 2011 The Physiological Society

Low birth weight followed by postnatal over-nutrition in the guinea pig exposes a predominant player in the development of vascular dysfunction

The association between intrauterine growth restriction (IUGR) and hypertension is well established, yet the interaction between IUGR and other pathogenic contributors remains ill-defined. This study examined the independent and interactive effects of fetal growth reduction resulting in low birth weight (LBW), and postnatal Western diet (WD) on vascular function. Growth reduction was induced in pregnant guinea pigs by uterine artery ablation. LBW and normal birth weight (NBW) offspring were randomly assigned to a control diet (CD) or a WD. In young adulthood, length-tension curves were generated in aortic rings and responses to methacholine (MCh) were evaluated in the carotid and aorta using wire myography. Relative to NBW/CD, aortae of NBW/WD offspring were stiffer, as determined by a leftward shift in the length-tension curve, yet the shift in the LBW/CD curve was considerably greater. Aortic stiffening was most severe in LBW/WD (slope: NBW/CD, 1.97 ± 0.04; NBW/WD, 2.16 ± 0.04; LBW/CD, 2.28 ± 0.05; LBW/WD, 2.34 ± 0.07). Maximal responses (Emax) to MCh were significantly blunted in the aorta of LBW/CD vs. NBW/CD (P \u3c 0.05) and in LBW/WD vs. NBW/WD offspring (P \u3c 0.05); but WD alone had no influence on MCh responses. Emax values for carotid responses to MCh were reduced in LBW/CD vs. NBW/CD (P \u3c 0.05). Thus, aortic stiffening was influenced more by LBW than by a postnatal WD and the most severe stiffening was observed in LBW/WD offspring. In contrast, blunted endothelial responses in LBW/CD offspring were not exacerbated by WD. IUGR may have a greater independent impact on vascular function than a postnatal WD

On-chip quantum interference between silicon photon-pair sources

Large-scale integrated quantum photonic technologies1, 2 will require on-chip integration of identical photon sources with reconfigurable waveguide circuits. Relatively complex quantum circuits have been demonstrated already1, 2, 3, 4, 5, 6, 7, but few studies acknowledge the pressing need to integrate photon sources and waveguide circuits together on-chip8, 9. A key step towards such large-scale quantum technologies is the integration of just two individual photon sources within a waveguide circuit, and the demonstration of high-visibility quantum interference between them. Here, we report a silicon-on-insulator device that combines two four-wave mixing sources in an interferometer with a reconfigurable phase shifter. We configured the device to create and manipulate two-colour (non-degenerate) or same-colour (degenerate) path-entangled or path-unentangled photon pairs. We observed up to 100.0 ± 0.4% visibility quantum interference on-chip, and up to 95 ± 4% off-chip. Our device removes the need for external photon sources, provides a path to increasing the complexity of quantum photonic circuits and is a first step towards fully integrated quantum technologies

Stochastic Variational Search for ΛΛ4^{4}_{\Lambda\Lambda}H

A four-body calculation of the $pn\Lambda\Lambda$ bound state, $^{\ 4}_{\Lambda\Lambda}$H, is performed using the stochastic variational method and phenomenological potentials. The$NN$,$\Lambda N$, and$\Lambda\Lambda$potentials are taken from a recent Letter by Filikhin and Gal, PRL{\bf 89}, 172502 (2002). Although their Faddeev-Yakubovsky calculation found no bound-state solution over a wide range of$\Lambda\Lambda$interaction strengths, the present variational calculation gives a bound-state energy, which is clearly lower than the$_\Lambda^3{H}+\Lambda$threshold, even for a weak$\Lambda\Lambda$interaction strength deduced from a recent experimental$B_{\Lambda\Lambda}(^{6}_{\Lambda\Lambda}{He})$value. The binding energies obtained are close to, and slightly larger than, the values obtained from the three-body$d\Lambda\Lambda$ model in the Letter.Comment: Corrected typos, added addtional calculations regarding a truncated to l=0 interaction model, 4 pages, 3 figure

The differential effects of low birth weight and Western diet consumption upon early life hepatic fibrosis development in guinea pig

Key points: Postnatal intake of a high saturated fat/high sugar diet, the Western diet (WD), is a risk factor for liver fibrosis. Recently, adverse in utero conditions resulting in low birth weight (LBW) have also been associated with postnatal fibrosis development. We demonstrate that suboptimal in utero conditions resulting in LBW are associated with changes in hepatic profibrotic genes in conjunction with minimal liver fibrosis in young non-overweight adult guinea pigs. Our results also indicate that WD promotes liver steatosis, enhanced expression of hepatic genes and proteins of the proinflammatory, profibrotic, cell death and collagen deposition pathways in conjunction with mild hepatic fibrosis. Our data highlight that pathways responsible for the initiation of a profibrotic state and ultimately hepatic fibrosis appear different depending upon the insult, an in utero-induced LBW outcome or a postnatal WD exposure. Postnatal intake of an energy dense diet, the Western diet (WD), is a strong risk factor for liver fibrosis. Recently, adverse in utero conditions resulting in low birth weight (LBW) have also been associated with postnatal fibrosis development. We assessed the independent and possible synergistic effects of placental insufficiency-induced LBW and postnatal WD consumption on liver fibrosis in early adulthood, with a specific focus on changes in inflammation and apoptosis pathways in association with fibrogenesis. Male LBW (uterine artery ablation) and normal birth weight (NBW) guinea pig pups were fed either a control diet (CD) or WD from weaning to 150 days. Significant steatosis, mild lobular inflammation, apoptosis and mild stage 1 fibrosis (perisinusoidal or portal) were evident in WD-fed offspring (NBW/WD and LBW/WD). In LBW/CD versus NBW/CD offspring, increased transforming growth factor-beta 1 and matrix metallopeptidase mRNA and sma- and Mad-related protein 4 (SMAD4) were present in conjunction with minimal stage 1 portal fibrosis. Further, connective tissue growth factor mRNA was increased and miR-146a expression decreased in LBW offspring, irrespective of diet. Independent of birth weight, WD-fed offspring exhibited increased expression of fibrotic genes as well as elevated inflammatory and apoptotic markers. Moreover, the augmented expression of collagen, type III, alpha 1 and tumor necrosis factor-alpha was associated with increased recruitment of RNA polymerase II and enhanced histone acetylation (K9) to their respective promoters. These data support a role for both LBW and postnatal WD as factors contributing to hepatic fibrosis development in offspring through distinct pathways

A simple and efficient numerical scheme to integrate non-local potentials

As nuclear wave functions have to obey the Pauli principle, potentials issued from reaction theory or Hartree-Fock formalism using finite-range interactions contain a non-local part. Written in coordinate space representation, the Schrodinger equation becomes integro-differential, which is difficult to solve, contrary to the case of local potentials, where it is an ordinary differential equation. A simple and powerful method has been proposed several years ago, with the trivially equivalent potential method, where non-local potential is replaced by an equivalent local potential, which is state-dependent and has to be determined iteratively. Its main disadvantage, however, is the appearance of divergences in potentials if the wave functions have nodes, which is generally the case. We will show that divergences can be removed by a slight modification of the trivially equivalent potential method, leading to a very simple, stable and precise numerical technique to deal with non-local potentials. Examples will be provided with the calculation of the Hartree-Fock potential and associated wave functions of 16O using the finite-range N3LO realistic interaction.Comment: 8 pages, 2 figures, submitted to Eur. Phys. J.

Soft-core baryon-baryon potentials for the complete baryon octet

SU(3) symmetry relations on the recently constructed hyperon-nucleon potentials are used to develop potential models for all possible baryon-baryon interaction channels. The main focus is on the interaction channels with total strangeness S=-2, -3, and -4, for which no experimental data exist yet. The potential models for these channels are based on SU(3) extensions of potential models for the S=0 and S=-1 sectors, which are fitted to experimental data. Although the SU(3) symmetry is not taken to be exact, the S=0 and S=-1 sectors still provide the necessary constraints to fix all free parameters. The potentials for the S=-2, -3, and -4 sectors, therefore, do not contain any additional free parameters, which makes them the first models of this kind. Various properties of the potentials are illustrated by giving results for scattering lengths, bound states, and total cross sections.Comment: 22 pages RevTex, 6 postscript figure